I think a legitimately good stand-up comic would have a shot in the Presidential race. I mean, it's absolutely absurd on its face, but when you boil it down to zingers and quick wit, a good stand up would crush. Get all your real info fed to you from some political think tank, and then just torch all other candidates with your stand up skills.
Chris Rock should really consider making Head of State a documentary.
Black Mirror made an episode on this very thing. The Waldo Moment. Pretty good one.