Great company, possibly revolutionary tech (pun intended) but the prelim data was released and the stock already exploded. $46B market cap is pretty steep. A typical price to sales for smaller pharma/biotech is around 6'ish.....so that assumes a future sales of $8B or so.
You can definitely make money on the stock and RVMD can become the next Vertex ($140B market cap), but investors should be prepared for some consolidation. Not saying a big price decline, but rather an extended period of flatlining as sales catch up.
As mentioned by RU206 - possible buyout candidate for a large pharma.