Not when it comes to National titles..I’d rather use since 2 platoon football ( 1964) and not all those leather helmet years..You could go back and compare all the final AP polls since 1939. That doesn't cover all the histories of the Big Ten and ACC, but at least it is a good sample.
You could compare all time winning percentages of teams in the conferences. That gets tricky because of so many new members on each side. But overall again, the Big Ten dominates.
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Oklahoma and Nebraska have 12 national titles since the AP formed (1936) more than the rest of the B1G..