Literally just closed on my first home 2 weeks ago. Went through Dave Ramsey's ELP program and found a great realtor. My advice here is find a realtor that you like. You get to choose so pick one that understands you and what you want.
-We went through our local credit union for lending. My advice here is to simply check around at a few different financial institutions to ensure you are getting a good interest rate. Try to go ahead and get pre-approved. Pre-qualified and pre-approved are 2 different things. Being pre-approved may alleviate some headaches that you could encounter when you get close to closing day.
-Make your realtor work for you. Tell him/her your lifestyle, what you're looking for in a house, etc. On the flip side, we went through hundreds of houses "virtually" (basically just on Zillow). This cut down on showing up to a home for showing and immediately not even liking it. It's a time saver. Suggest the homes that you do like to your realtor.
-It's cliche but true, don't have the nicest house in the neighborhood. In essence, this is an investment.
-When you get ready to offer, get your realtor to get comps of some other houses near that house and see what they sold for. The only complaint I had on our realtor is that she didn't really offer any advice on what we should offer. (I know that the lower the price, the less commission she gets, but still). If the house is 175,000, don't be afraid to offer something like 150 or 160. You never know. If the house appraises at 175, technically you get 10 to 20k of instant equity if the seller accepts your offer.
-When it's time for the inspection, do some research and get an inspector that's not in any way affiliated with your realtor. I'm not saying all realtors are bad. But they could easily recommend an inspector that they know will not come up with too many problems with the house because the realtor wants to get the house to closing to get their commission. On the flip side, they probably give the inspector a cut on the deal.
-The day leading up to closing will drive you crazy. My credit union literally waited until the last day to start asking for documents. Luckily I had them ready to go. It was probably the most stressful thing I've done in a while.
That's all I got right now. I'll add some more if I think of anything else. Good luck!