When COVID first showed up everybody received plaquenil and azithromycin. At no point did it feel like it was helping. Not to say that every patient I saw died. Of course not. Some people got over it, but the ones who got sick responded to nothing we did. I was not shocked when the studies started to come out that showed no benefit. We stopped using it. Out only real treatment at that time was plasma. It was hit or miss if we could get it for each patient and usually was not rapidly available. I noticed no difference in the clinical course of those patients without plaquenil/azithromycon compared to those who had received it.
We now give Remdesivir and Decadron to anyone requiring fio2. Usually plasma as well. We also consider Remdesivir in certain situations. I am in no way saying this is a miracle cure: people are still dying. I do feel for the first time during all this That we have a treatment regimen that is helping some of the patients. We have kept a significantly larger portion out of the ICU and off the ventilator.
The above is my personal experience. If a definitive study came out that showed plaquenil worked, I would give it in a heartbeat regardless of how I feel about it. I welcome any treatment that will help. The science as well as my personal experience says plaquenil does not.
Thanks for what you do
And for the medical Lesson.