It's going to be a bloodbath after the round of 32, I've never seen this many legitimate contenders in one year. I wouldn't fuss too much with who the top 4 seeds in a region are, they're all going to be very tough.
I keep telling myself that I'm not rooting for Syracuse or Carolina today, and that I'm just rooting for the winner of the Nova-OU game on Monday. It makes me feel better.