Nobel Prize-winning immunologist interviewed...

[Maroon Eagle]

He expects the UK to have a vaccine by September.

Link: Here.

It was published almost a week ago so apologies for Germans in the off chance it was already shared here.

 

[Dawgzilla]

He expects the UK to have a vaccine by September.

Link: Here.

It was published almost a week ago so apologies for Germans in the off chance it was already shared here.

But has he won a Noble prize?

 

[11thEagleFan]

Would love to read it but it’s behind a pay wall. Summary?

 

[Dawgpile]

[FONT=suecanano_regular]You have reached an article available exclusively to subscribers[/FONT]

 

[Maroon Eagle]

He really likes what the Jenner Institute is doing...

He says that they’re testing in humans and there are 60 million doses being rolled out in the UK for September— incidentally the same testing process as was the Ebola vaccine.

For those over 60, the vaccine isn’t a complete fix so all folks younger than 60 will need the vaccine for herd immunity.

 

[Raiderdawg.sixpack]

He’s a true expert in immunology, Nobel or not.

I hope he is correct. Definitely would be an achievement if we get a safe & effective vaccine this fast. I talked to a virologist directly working on this earlier this week & it was not a very optimistic conversation.

My take is to not expect a vaccine soon, but be pleasantly surprised if we get one.

 

[Shmuley]

In your opinion, what are the chances that this virus mutates into a less virulent, less deadly state?

 

[Maroon Eagle]

Yep. I hope he’s correct too.

In the interview, he says around 600 folks have been vaccinated. And they’re checking to see if there are any bad side-effects— admitting he’d be surprised if it happens. In the meantime, they’re manufacturing doses to be ready by September.

 

[Bcash2]

That's for journalists*

 

[SheltonChoked]

He expects the UK to have a vaccine by September.

Link: Here.

It was published almost a week ago so apologies for Germans in the off chance it was already shared here.

This is good news.

 

[Bcash2]

This link should be readable for all: http://archive.is/RkHy6

If your browser doesn't like the link and gives a warning, ignore it.

 

[Raiderdawg.sixpack]

I think it’s probably happening already & we don’t realize it.

I know of a community-acquired infection in a mid-Atlantic state that when they sequenced it compared to their reference strain from Washington state, it was noticeably different. It wasn’t the same or just 1 mutation off, it had multiple mutations differences.

The strains that have been sequenced so far seem to have a highly conserved spike protein. Basically, a lot of the mutations are not occurring in the protein that binds to our cells. There are several mutations though that allow us to trace the evolution path. If the strain is sequenced, you can tell if the lineage was China to West coast or China-Italy-New York. I am sure there maybe other evolutionary paths.

We know this virus has 29 proteins. A mutation in the RNA may be silent (doesn’t change much) or it could be significant. As these strains evolve, we could definitely have a SARS-CoV-2 strain circulating that is infectious but not very pathogenic and basically acts almost like a vaccine strain. We could have one mutate into a more virulent or pathogenic. We may have it eventually evolve to where at catching 1 may not provide protection to another strain. We don’t really know what’s happened. In a perfect world, a highly contagious, less virulent strain emerges that infects everyone, causes a robots immune response and then people are protected against other strains because they haven’t evolved so much yet. The virus is remarkably stable for having passed through so many people, but we really don’t have a full picture on the evolution yet - we just keep getting small pieces of the puzzle.

 

[johnson86-1]

I think it’s probably happening already & we don’t realize it.

I know of a community-acquired infection in a mid-Atlantic state that when they sequenced it compared to their reference strain from Washington state, it was noticeably different. It wasn’t the same or just 1 mutation off, it had multiple mutations differences.

The strains that have been sequenced so far seem to have a highly conserved spike protein. Basically, a lot of the mutations are not occurring in the protein that binds to our cells. There are several mutations though that allow us to trace the evolution path. If the strain is sequenced, you can tell if the lineage was China to West coast or China-Italy-New York. I am sure there maybe other evolutionary paths.

We know this virus has 29 proteins. A mutation in the RNA may be silent (doesn’t change much) or it could be significant. As these strains evolve, we could definitely have a SARS-CoV-2 strain circulating that is infectious but not very pathogenic and basically acts almost like a vaccine strain. We could have one mutate into a more virulent or pathogenic. We may have it eventually evolve to where at catching 1 may not provide protection to another strain. We don’t really know what’s happened. In a perfect world, a highly contagious, less virulent strain emerges that infects everyone, causes a robots immune response and then people are protected against other strains because they haven’t evolved so much yet. The virus is remarkably stable for having passed through so many people, but we really don’t have a full picture on the evolution yet - we just keep getting small pieces of the puzzle.

See, this is why the so called "experts" are so worthless. Something like 95% of sixpack posters definitely know what's happened and what's going to happen while the "experts" twiddle their thumbs.**

 

[Shmuley]

Excellent info. Very much appreciated. Here’s hoping this mutation thing goes in the right direction quickly